According to the Jerusalem Post, the victims were a 24-year-old woman, a 73-year-old man, and a woman in her 60s. Three others were seriously wounded, and two others were in light to moderate condition.
One of the men murdered was identified as Rabbi Elimelech Wasserman, a judge in the rabbinical court in Ashdod.
Video showed the two terrorists from east Jerusalem, carrying an M16 and a handgun at the Givat Shaul junction, getting out of a car and firing at civilians at a bus stop while people fled the scene.
The two terrorists were shot and killed by law enforcement and a civilian who was at the scene, as well as an IDF soldier who was heading back to base after a break from service in Gaza.
The terrorists were identified as Murad and Ebrahim Nemer, brothers from Sur Baher in east Jerusalem who have ties to Hamas.
Murad had been a prisoner in Israel from 2010-2020 due to terrorist activity.
National Security Minister Itamar Ben-Gvir said after arriving at the scene, "This event proves once again how much we must not show weakness, how much we should talk to Hamas only through the gun sight, only through war. My stance about the ceasefire is known, Hamas must not be allowed to speak to us with two voices."
He added, "Weapons save lives, we see it time after time, wherever there are weapons, citizens, policemen, soldiers, save lives. And this weapon can save us and it proves itself time and time again."
US Ambassador to Israel Jack Lew posted on X, "Abhorrent terrorist attack in Jerusalem this morning. We unequivocally condemn such brutal violence. My thoughts are with the families of the victims and I offer my sincere condolences to all those affected."
The attack comes as Israel and Hamas negotiated an extension of a ceasefire to a 7th day.